TB-500 drives cellular mobilisation, particularly promoting the migration of keratinocytes, endothelial cells, and stem/progenitor cells to sites of tissue disruption, while simultaneously suppressing inflammatory and apoptotic signalling
The resulting inflammation creates a painful cycle where swelling leads to more impingement which causes more swelling
Preclinical studies suggest good tolerability, but comprehensive human trials are needed to establish safety profiles
Full reconstitution guide Advanced calculator Dosing & Reconstitution Guide A single practical dilution with accurate once-daily dosing, step by step Standard / Gradual Approach (5 mL = 100 mg/mL) Reconstitute: Add 5.0 mL bacteriostatic water to one 500 mg vial final concentration 100 mg/mL (1 unit = 1 mg)
A large percent of adults with lupus have an increase of type I interferon
10.1515/BC.2002.208 [DOI] [PubMed] [Google Scholar] Aller M