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women must use reliable contraception and discontinue treatment at least two months before planned conception

The reason is a complex mix of the cost of the drug itself, GLP-1s impact on health outcomes, and the fact that most preventive health measures do not reduce federal health spending

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Many proteins contain small amounts of DPP-4 inhibitors, and amino acids that can trigger GLP-1 production

Reduced appetite typically appears within 3-4 weeks