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Cells were lysed in PRO-PREP (iNtRON Biotechnology, Seongnam, Korea)

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Endogenous GLP-1 acts on paraventricular nucleus to suppress feeding: projection from nucleus tractus solitarius and activation of corticotropin-releasing hormone, nesfatin-1 and oxytocin neurons

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Semaglutide works by mimicking a natural hormone known as glucagon-like peptide 1 (GLP-1), which helps regulate appetite and insulin production

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