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The most common side effects were gastrointestinal events

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Histopathological assessment further revealed pronounced degenerative changes in the testes, epididymis, seminal vesicles, and prostate

These antibiotics accumulate within the endolymph, preferentially damaging outer hair cells in the basal cochlea, which results in high-frequency hearing loss, often the first detectable sign of aminoglycoside-induced ototoxicity (OSullivan et al