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A 2019 review in Aging Cell noted that metformin reduced circulating TNF-alpha by 17% and IL-6 by 24% in a pooled analysis of 664 patients with type 2 diabetes across four randomized controlled trials [9]

Delta sleep-inducing peptide and Deltaran: Potential approaches to antistress protection. Neuroscience and Behavioral Physiology 38 1 (2008): 953957

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Attrubys approval was supported by positive results from the Phase III ATTRibute-CM, where the transthyretin stabilizer significantly reduced death and cardiovascular-related hospitalization, and improved quality of life

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