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Treatment of hypertension during pregnancy as a replacement for ACE inhibitors & ARBs The patient can be switched back to an ACE inhibitor or ARB once pregnancy is over Notes: Methyldopa is the L-isomer of alpha-methyldopa References: Benowitz NL (2024): Antihypertensive Agents (Chapter 11)

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Sanyal AJ, Kaplan LM, Frias JP et al (2024) Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial

Retatrutide is a 39-amino-acid synthetic triple-receptor agonist peptide that activates GLP-1, GIP, and glucagon receptors simultaneously