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Data availability Data sharing is not applicable to this article as no new data were created or analyzed in this study

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Subcutaneous injection delivers the intact pentapeptide into systemic circulation within 3045 minutes, bypassing gastric and intestinal enzymes that would otherwise cleave peptide bonds

AMPK/PGC1 activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis

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Topical applications are used primarily for skin benefits but may not significantly affect overall glutathione levels