In addition to mimicking GLP-1, tirzepatide mimics another gut hormone called gastric inhibitory polypeptide, or GIP, that scientists believe has a similar effect on the body as GLP-1
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The neurotrophic agents capable of facilitating synaptogenesis and neurogenesis include nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4 [34,35]
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Your cells may stop responding as strongly to the hormone your gut produces, much like insulin resistance develops in type 2 diabetes