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Jin L, Kimura S, Zhou Y, Kuroda J, Asou H, Inaba T, Andreeff M , Miida T, Tabe Y

PI3K/Akt activation of the survival pathway in beta cells

It can be administered as a topical cream, spray, injection, or oral supplement

Metabolite concentrations were estimated using LCModel [51]

The cell pellets were washed with PBS and alkylated for 15 min at room temperature (RT) under denaturing conditions in 200 l of UCE-IAM buffer, consisting of 8 M urea, 1% (w/v) CHAPS, 1 mM EDTA, 200 mM TrisHCl pH 8.0 and 100 mM IAM as described (Rossius et al., 2018)

When sex emerged as a significant factor, separate ANOVAs were performed for males and females