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J Am Soc Nephrol JASN

2002;8(11):BR439-443

However, alternative oxygen concentrations, such as 1% or 5%, were not investigated, leaving it unclear whether the effects observed are specific to the 3% condition or indicative of a more general hypoxia-dependent response

The concept that an increase in the LBP may increase ligand promiscuity was further supported by biochemical studies in which threonine was replaced by the larger amino acid aspartic acid, which prevented androgen binding, presumably by steric hindrance, making the mutant receptor unresponsive to androgen activation 166

esculentum plants (Li et al., 2012)

In addition, probiotics produce various antioxidant metabolites, such as GSH and folate