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Wang X, Chen XX, Zhou WQ, Men HB, Bao T, Sun YK, et al

BioMed Research International, 2015

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First, all compounds undergo loss of the residue of -linked glutamic acid as pyroglutamic acid, although with different intensity, but with very similar onset energy between the physiological substrates of the enzyme, glutathione and glutathione disulfide and metal-bound glutathione conjugates

Parkin inhibits iron overload-induced cardiomyocyte ferroptosis by ubiquitinating ACSL4 and modulating PUFA-phospholipids metabolism