To view digital features for this article, go to Introduction Diabetes care is evolving towards the personalized medicine approach, moving beyond the basic assumption that diabetes is solely a consequence of -cell dysfunction in a single hormone, insulin [1,2,3,4]
Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis
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The resulting reactive aldehydes, such as 4-hydroxy-2-nonenal (4-HNE) and malondialdehyde (MDA), not only form adducts with DNA and proteins but also act as secondary messengers that modulate signaling and cell death [41, 42]
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During the process of carcinogenesis, lysosomes significantly transfer from the perinuclear region to the peripheral cytoplasm, which led to enhanced lysosomal exocytosis 28
