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However, activating microglia using intraspinal injection of zymosan, a TLR-2 agonist, showed oligodendrocyte loss without increase in NG2 + cell proliferation (Schonberg et al., 2007)

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From the study of Halme et al

Conversely, after the treatment is completed, the hydrogel should be able to degrade and be eliminated from the body in a timely manner to avoid remaining in the body and causing adverse reactions

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