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There are currently 4 DPP-4 inhibitors approved by the United States (U.S.) Food and Drug Administration (FDA): sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), and alogliptin (Nesina)

(PubMed) Hudson S, Tabet N

Consequently, the development of new treatment methods is particularly urgent

It will therefore be interesting in future studies to determine the contribution of dietary carnitine to histone acetylation and HR-proficiency and whether modulating dietary carnitine would affect response of tumors to DNA damaging agents or even slow the development of tumors

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