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L-arginine affects sleep because its a nitric oxide precursor

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GIP may further regulate food intake when added to GLP-1 per nonclinical studies

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Tirzepatide has shown promising cardiovascular and heart failure benefits, including positive outcomes in people with obesity and heart failure with preserved ejection fraction

[DOI] [PubMed] [Google Scholar] 13.The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions