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The claim holds water according to a 2019 meta-analysis, whose authors note that a berberine-silymarin complex can indeed produce "satisfactory results" in increasing berberine's bioavailability.43 The same meta-analysis examined the metabolic effects of combining berberine with silymarin

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The FDA has also flagged BPC-157 in the context of bulk substances that may pose significant safety risks, especially in compounding environments

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