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Mainwaring GW, Nash J, Davidson M, Green T

Personalized medicine, which tailors treatment plans to individual patient needs, is an emerging trend that holds promise for better managing side effects, including skin sensitivity

The gap between trial and real-world tirzepatide vs semaglutide outcomes comes mostly from discontinuation and under-titration: only 25.9% of tirzepatide users reach 15 mg in practice, versus 83.5% of semaglutide users reaching 2.4 mg in the trial

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Individual results vary, but outcomes are clinically predictable with proper monitoring, lifestyle support, and attentive follow up