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The safety and effectiveness of Wegovy HD (semaglutide) injection 7.2 mg have not been established in pediatric patients

These changes occurred alongside reductions in inflammatory cytokines and adhesion molecules

"However, it is also notable that the highest tirzepatide dose was associated with increased gastrointestinal adverse events," Karagiannis added

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Semaglutide is known for delivering faster weight loss, while metformin tends to result in slower, more gradual changes

Both peptides offer unique therapeutic advantages with minimal side effects and established safety profiles