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From reconstitution to administration

The Mann-Whitney U test was used to compare significant differences between continuous variables

Then, we fed a culture of gut microbes with l-carnitine together with a pomegranate extract, which is rich in polyphenols

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The dosing regimen may depend on the specific patient population, with low-dose, long-term supplementation possibly being sufficient in healthy individuals, whilst patients with end-stage renal disease probably need higher dosages and ideally in combination with folate