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In hepatocellular carcinoma models induced by DEN combined with either high-fat/high-carbohydrate or low-fat/low-carbohydrate diets, lean m/db mice, and MCD- or CDE-induced liver injuryas well as in human models, exenatide activation of the GLP-1RcAMPPKAEGFRSTAT3 pathway suppressed oncogenic signaling, limited tumor cell growth, and enhanced apoptosis, resulting in a marked reduction in tumor progression (Zhou et al., 2017)

10.3390/nu11030653 [DOI] [PMC free article] [PubMed] [Google Scholar] Sanlier, N

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doi:10.1002/phar.2688 67