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10.3389/fbioe.2020.00822 3 BattistiniL.BugattiK.SartoriA.CurtiC.ZanardiF

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Given that myocardial infarction is accompanied by metabolic stress and AMPK activation, it can be inferred that AMPK activation leads to PINK1-Parkin mitophagy, suggesting that mitophagy decelerates the progression of necrotic death in cardiomyocytes [108]