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doi: 10.1161/CIRCULATIONAHA.117.028136 22 ChangWZhuFZhengHZhouZMiaoPZhaoLet al

No statistically significant difference was detected in forced vital capacity (FVC) or self-sufficiency

Because digestion takes longer, some people may experience gastrointestinal effects such as nausea, vomiting, bloating, or stomach discomfort while adjusting to treatment

Importantly, patients considering therapy changes should consult qualified clinicians

SGLT2 inhibitors have demonstrated robust reductions in hospitalisation for heart failure across risk groups, with cardiovascular death benefits most clearly established in heart failure trials

[1] [2] Gastrointestinal tolerability must be thoroughly assessed before dose advancement