retatrutide phase 2 trial results weight loss Retatrutide: What It Is & How This New Drug Works 28.7% Weight Loss in New

Secondary outcomes examined worsening of depression or anxiety separately, substance use disorders, and self-harm incidents

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Asano et al

Adequate Protein Intake Target: 1.6-2.2 grams of protein per kilogram of body weight per day 4 For most people, this translates to: 150 lb person: 110-150g protein/day 200 lb person: 145-200g protein/day 250 lb person: 180-250g protein/day This is significantly higher than standard recommendations (0.8g/kg) because during caloric restriction, your protein needs increase to: Prevent muscle protein breakdown Support muscle protein synthesis Maintain metabolic function Support satiety and appetite regulation 2

Phase 2 (NEJM 2023): 24.2% mean weight reduction at 48 weeks (12mg dose)

New combinations and oral GLP-1 options The field of GLP-1 therapies is rapidly evolving, with exciting developments that enhance convenience and efficacy