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Signs suggesting cycle extension include continued gradual improvement at cycle end, incomplete resolution of primary concerns, and recent flare or setback

The treatment also appeared to ameliorate cardiovascular risk, as endothelial function improved by the end of the treatment period

Patients often experience lower A1C levels, reduced fasting glucose, improved insulin sensitivity, decreased inflammation, and better cardiovascular risk profiles

10.1111/apa.12791 16 ElgassK.PakayJ.RyanM