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Shandong Jingtang Chemical - Peptides
None of the change reached significance, likely due to the limited sample size (Supplemental Table S3B)
The interaction of AGEs with their receptor (RAGE) on VSMCs triggers intracellular oxidative stress by activating the transcription factor NF-B (Yamagishi, 2011
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Thus, our data show that Phe and its major metabolites accumulated in PKU provoke extensive DNA damage in glial cells probably by ROS formation and that L-car may potentially represent an adjuvant therapeutic agent in PKU treatment
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