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The highest pLDDT value of 70 is found in D909 (on a scale of 0100), which corresponds to a ~0.7 probability of correct angles

The occurrence of mHE predicts the onset of OHE [20] and adversely affects survival [21]

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DOI: 10.1016/j.peptides.2005.01.029 Clinical Development Afamelanotide and EPP Afamelanotide (MT-1), delivered as a subcutaneous slow-release implant, has been studied in multiple randomised controlled trials in patients with erythropoietic protoporphyria (EPP)