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Doctors are beginning to prescribe GLP-1s for younger children, but its off-label, meaning the drug hasnt been formally tested and approved for that age group

That incremental GCGR effect could theoretically be achieved by titrating retatrutide monotherapy instead, without the compounded risk

Unlike natural GLP-1, which has a very short lifespan in the body, GLP-1 agonists are designed to resist degradation by DPP-4, giving them a longer half-life

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Most compounded GLP-1 programs are direct-pay and not billed through insurance

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