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Retrieved from Tamayo-Trujillo, R., Ruiz-Pozo, V

This ensures they are not only effective but also safe for use under recommended conditions

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Unfused albumin variants or GLP-1 albumin fusions (2 mg/mL) were loaded onto the column in a pH gradient from pH 5.5 to pH 8.8 by injecting a gradual mixture of 20 mM MES/HCl, 140 mM NaCl (Sigma-Aldrich) (pH 5.5) and 20 mM Tris/HCl, 140 mM NaCl (Sigma-Aldrich) (pH 8.8) at a flow rate of 0.5 mL/min for 110 min at room temperature

doi: 10.3803/EnM.2014.29.4.536 70 KrnerMStckliMWaserBReubiJC

32 Shor et al used a nationwide Canadian EHR database to compare 46,334 patients taking GLP-1 RAs with 92,668 controls over a follow-up period of 6 months to 3 years