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doi: 10.1016/j.aquabot.2018.12.008 71 WangW.ShenZ.SunX.LiuF.LiangZ.WangF.et al

A 2022 review found oxidative stress may lead to the progression of: neurodegenerative diseases, such as Alzheimers heart disease chronic kidney disease cancer type 2 diabetes obesity Other characteristics from a 2020 review of carotenoids include: anti-inflammatory agent immune system-boosting increasing bone density Lutein may also help prevent nonalcoholic fatty liver disease (NAFLD)

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Recently published lines of evidence suggest a role for pannexin 1 (Px1) as one component in the release of ATP from RBCs ( in vivo and into the supernatant in vitro ( via adenosine receptors promotes deoxygenation of sickle hemoglobin and in turn (HbS) polymerization and RBC sickling