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A 2017 review found biotin supplementation improved nail thickness in 63% of subjects (Patel et al

(1998) the gold-standard comparison A 12-week randomized trial enrolled 67 women with moderate-to-severe facial aging and compared four topical formulations: a copper peptide cream, a vitamin C cream, a melatonin cream, and tretinoin

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BPC-157 (Body Protection Compound-157) is an artificial peptide composed of 15 amino acids, based on a natural protein that is present in the stomach, and that is studied due to its healing and regenerative effects

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PMID 15919781