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The authors described these structural models as the basis for rational development of p53 inhibitors targeting the senescent cell biology field and diseases linked to cellular senescence including cancer
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The current body of research suggests several key mechanisms: Angiogenesis: It appears to promote the formation of new blood vessels, a critical, non-negotiable element for delivering nutrients and oxygen to damaged tissues for repair
It is foundational to nearly every physiological system, influencing oxygen delivery, mitochondrial energy production, cellular signaling, and tissue repair
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