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June 1999, 11 (6): 11531164

While missing the occasional dose is not likely to affect your weight loss journey massively, missing doses regularly or missing enough doses that you have to restart treatment at a lower dose will increase the time it takes to reach your weight loss goals

The Role of Altered Mitochondrial Metabolism in Thyroid Cancer Development and Mitochondria-Targeted Thyroid Cancer Treatment

In studies done with GLP-1 agonist medications, patients lost more weight while taking the medication, participating in behavioral therapy, and eating a low-calorie diet than patients who followed a low-calorie diet and participated in behavioral therapy alone

Some proposed mechanisms include reduced inflammation and effects on the cardiovascular system including natriuresis (increased sodium excretion by the kidneys), though these require further research confirmation

Whats the maximum calorie deficit I should aim for on a GLP-1