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It is not trivial

Arch Intern Med 159:26472658 Holt LE Jr, Albanese AA (1944) Observations on amino acid deficiencies in man

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Oral formulations have been investigated for their potential effects on the stomach, intestines, and gastrointestinal lining while also being evaluated for broader systemic activity

Accordingly, we proposed that a large dose of L-carnitine administrated intravenously was responsible for alleviating starvation discomfort including persistence fatigue and intense hunger over the short term

Modifying receptor activity influences a range of functions