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Antithrombotic Effects GLP-1 agonists reduce cardiovascular events through several mechanisms previously summarized to include improved glycemic control, weight loss, lowering blood pressure, lipid lowering, reduced atherogenesis, attenuated vascular inflammation, improved endothelial cell function, vasodilation, and direct cardiovascular protective effects [88, 89]

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doi: 10.1016/j.intimp.2025.114430 115 DasNKSchwartzAJBarthelGInoharaNLiuQSankarAet al

When rapid weight loss is medically necessary : Before bariatric surgery, for joint replacement candidacy, or when weight directly threatens cardiovascular health

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