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Research from the STEP clinical trials demonstrates that participants using semaglutide lose significantly more weight than those on placebooften 15% to 22% of body weight over 68 weeks

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Recently, to ensure the safety of GLP-1 RA on sarcopenia, a clinical randomized multicenter trial of bimagrumab, an antibody blockade of activin type II receptor inhibitor, alone or in addition to subcutaneous semaglutide is now ongoing (NCT05616013) [113]

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