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Cranial MRI in patients with FMRD may show enlarged ventricles and subarachnoid spaces [86], abnormally high signal intensity in the periventricular white matter, cerebral atrophy, delayed formation of myelin sheaths, thinning of the corpus callosum, and an abnormally small brainstem [87]

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Dosing chart at 10 mg/mL concentration (6 mL BAC water) This is the most common concentration for the 60 mg vial

Transduced quizartinib-resistant MOLM-14 cells 80 were selected in puromycin for 57 days and cultured for an additional 10 days before assessing overexpression of MTA1 by western blotting and panobinostat sensitivity

Dosing frequency is not one-size-fits-all

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