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Limited long-term human safety data for most compounds, with evidence generally drawn from short trials, animal studies, or research on a different indication

A following study identified the specific astrocyte subpopulation (GFAP low , AQP4 + , CD63 + ), verified in both humans and mouse AD models, enriched in early AD and diminished in later stages (Wei et al., 2024)

Microbiol Spectr 202210(4):e0173022

Valued at approximately USD 1.2 billion in 2023, projections indicate a compound annual growth rate (CAGR) of 8.5% over the next five years

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