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The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 6-hydroxydopamine (6-OHDA), and 5-S-cysteinyl-dopamine (CysDA) models each target dopaminergic neurons and increase oxidative damage to the brain, providing valuable insight to the efficacy of mitigating oxidative stress as a mechanism of sulforaphanes neuroprotective effects

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Perhaps the most rigorous large-scale estimate of disease prevalence is provided by the RAND Interstitial Cystitis Epidemiology (RICE) study, a US population-based telephone survey