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After receiving FDA approval for use, these GLP-1 (glucagon-like peptide 1)- based drugs have been described as game changers in the fight against obesity

Factors related to diabetes, including neuropathy affecting the nerves that control the gastrointestinal tract [10], [11] and changes in gut motility [12], can contribute to the development of PI, making the problem more severe and widespread

Severe gastrointestinal symptoms may lead to dehydration and acute kidney injury

For these reasons, GLP-1 microdosing should only be considered under the supervision of a licensed healthcare provider who can guide dosing decisions and monitor safety over time

Physiol Behav (2016) 159:729

And does it work better for weight loss than Ozempic and Wegovy