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IGF-1 plays a central role in tumor development by stimulating proliferation and inhibiting apoptosis in cancer cells. Pollak, Nature Reviews Cancer Acromegaly-Like Symptoms (Rare) In extremely high or prolonged dosesespecially when stacked with HGHIGF-1 may contribute to: Bone thickening (jaw, forehead, hands) Enlarged soft tissue Headaches or carpal tunnel symptoms These side effects mimic acromegaly , a condition caused by excessive GH/IGF-1 signaling

For more information on nausea and vomiting, visit: Most episodes resolve within 24-48 hours with clear fluids and rest, but persistent symptoms lasting over 3 days or signs of severe dehydration require medical evaluation

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Risk of anesthesia