According to Lillys release, the trial met its primary endpoint: participants titrating up to the highest orforglipron dose lost 27.3 lb (12.4%) of body weight at 72 weeks versus about 0.9% weight loss with placebo
Aslam B, Bin Zafar MD, Changez MIK, Abdullah M, Safwan M, Qamar B, et al
In a blog post, Reitano said the company became increasingly aware of patients' challenges with getting access to these new obesity treatments
You can get a rough estimate of whether you're carrying a risky amount of visceral fat by measuring your waist circumference, Kessler says
Are open to using compounded GLP-1s and comfortable with the fact that theyre not FDA-approved
Clinical trial context: According to the manufacturer, the OASIS 4 trial showed approximately 13-14% average weight loss over 64 weeks, with higher results (up to 16.6%) reported among participants who adhered closely to the treatment protocol