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Although the violations observed in the warning letters are easily understood, the letters reveal two important lessons that companies sometimes take too long to learn

10.1096/fj.201701460RRR 134 YangL.GuoY.HuangM.WuX.LiX.ChenG.et al (2018)

Contraindications and cautions include asthma (glutathione may trigger bronchospasm in sensitive individuals), platinum-based chemotherapy (glutathione may reduce drug efficacy), and certain genetic variations affecting cysteine and sulfur metabolism

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Individuals with conditions that affect their small intestine, such as Crohns disease and Celiac disease, may benefit from B12 supplementation, as well as those individuals who are on medications that affect B12 absorption, says Gans

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