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Series b, Psychological Sciences and Social Sciences, 55 , S108S116

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Panel A presents the 3D structure and 2D interaction map of ethacrynic acid, a well-established GSTP1 inhibitor

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Acetylation by CBP/p300 decreases the DNA-binding ability and nuclear localization of FOXO1 and FOXO3, thereby reducing their transcriptional activity and ability to induce autophagy