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4B is described a typical time course obtained after the optimization of previously cited reaction parameters

Sep 2021;203(7):3793-3802

Therefore, there is a pressing need to explore alternative therapeutic approaches

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Because the severity of short stature was highly variable (baseline height SDSs ranged from 9.4 to 1.3), some patients did not meet the specifications for height SDS outlined in the product monograph

Data availability The analyzed data supporting the findings of this study are available within the article and its Supplementary Information file