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Because amylin signalling is closely linked to meal termination, satiation, and brainstemhypothalamic regulation of food intake, amylinGLP-1 co-agonism may reshape eating experience through mechanisms that partly overlap with, but are not identical to, classical GLP-1R agonism

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Beyond the Scale: Cardiometabolic Promise In the Lancet trial, low-density lipoprotein cholesterol fell by 1619 %, and C-reactive protein by 28 %, hinting at cardiovascular-risk attenuation