Known inhibitors of TGRs/TrxRs, which include metal complexes and compounds containing Michael acceptors or oxadiazole oxides 19,23,24 , usually react with Sec and Cys residues and other biogenic nucleophiles irreversibly
Some of this content is machine-translated and may not be completely accurate
A. V. Arutjunyan, I. G. Popovich, L. S. Kozina, and G. A. Ryzhak, Peptide Regulation of Ageing: From Experiment to Practice, Bentham Science Publishers Ltd., Feb. 2025. doi: 10.2174/0118746098346230250116065407
Phillips MI, de Oliveira EM
GLP-1 agonists, on the other hand, have gained prominence in diabetes management due largely to the impact on reducing hemoglobin A1c and cardiovascular risk
The authors are also thankful to Medimax Pharmaceuticals, Amritsar, India, and Jackson Laboratories Pvt