glp-1 agonists vs bariatric surgery weight loss comparison Comparing GLP‑1 Drugs With Other Methods: Diet & Exercise, Surgery, and Lifestyle Programs -Pros & Cons GLP-1 vs Bariatric Surgery Study:

while significant pharmacokinetic interactions with psychiatric medications are not generally expected, GLP-1 agonists may affect absorption of some oral medications due to delayed gastric emptying Discuss realistic expectations regarding weight loss and diabetes control to avoid disappointment that might affect mood Ensure adequate support systems are in place, including regular contact with healthcare providers Discuss pregnancy plans as these medications are not recommended during pregnancy or breastfeeding

& Dyess, G

Treatments commonly used to treat mitochondrial disease have been found to improve both core and associated ASD symptoms

This is the concept of drug repurposing, which is becoming increasingly prevalent, particularly from an economic standpoint [151]

doi: 10.1056/NEJMoa1616011

The catch worth stating up front: there are no peer-reviewed studies on PDA as a distinct molecule and no human trials, so those numbers are extrapolation, not PDA-specific evidence