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Iron accumulation drives the Fenton and Haber-Weiss reactions, generating ROS that induce lipid peroxidation, leading to oxidative damage to subcellular structures (88)

This milestone demonstrates that the medication and lifestyle changes are creating lasting metabolic adaptation, not temporary restriction

L-Carnitina: a cosa serve La L-carnitina una sostanza naturalmente presente nel nostro organismo, coinvolta nel trasporto degli acidi grassi nei mitocondri , dove vengono convertiti in energia

The dosage and treatment duration should be determined by a healthcare professional based on the individual's needs, medical history, and response to treatment

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Figure 1 shows the action sites of SGLT2 and RASS inhibitors and the potential synergistic mechanism of their combined therapy in T2DM