Based on the pilot study findings, final adjustments were made to the survey instrument to enhance its reliability and validity
Disadvantages include the lack of standardized protocols and regimens and of clinical and histologic response criteria.111 Furthermore, residual hyperpigmentation following treatment may be confused with recurrence.119 In conclusion, the use of imiquimod should be reserved for cases in which surgery and other nonsurgical treatments such as radiation therapy are contraindicated, at least until further evidence is available on its efficacy and safety.7 Imiquimod can be used as adjuvant therapy before surgery to reduce tumor size108,113 or after surgery to treat extensive melanoma in situ around the lesion excised.120 Some authors have recommended its use in recurrent LM following conventional excision or Mohs micrographic surgery, in cases with positive margins (as adjuvant therapy), or to prevent recurrence.37,100,121,122 Other Nonsurgical TreatmentsAzelaic Acid Azelaic acid (C9 dicarboxylic acid) 20% in cream or 15% to 35% in ointment has been used to treat LM since the 1970s
2016;244Pt B:28091
We recommend informing any doctor who prescribes you an antibiotic that you are currently on a GLP-1 medication
3-O-Ethyl Ascorbic Acid Stable, Deep-Penetrating Vitamin C regular L-ascorbic acid (vitamin C) oxidizes rapidly and is difficult to stabilize
10.1007/s40291-018-0352-x 132 RossignolD
