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The key milestones include: exenatide approval (2005), liraglutide approval (2010), semaglutide injection approval (2017), oral semaglutide with SNAC approval (2019), orforglipron cryo-EM structure published (2020), orforglipron Phase 2 results in NEJM (2023), orforglipron Phase 3 ATTAIN-1 results in NEJM (2025), and FDA regulatory submission (2025)

Psychogenic Polydipsia Psychogenic polydipsia (PPD) (also known as primary polydipsia) is excessive and volitional water intake commonly patients with severe mental illness and/or developmental disability

Policy noticed 1/1/2019 for effective date 4/1/2019

Compounded medications, while legal and legitimate, dont go through FDA approval processes

If you imagine a public health campaign to get more people onto AUD medication, it would be a stunning achievement if you were able to more than triple the usage rate over 5 years and that may be what has already happened inadvertently

Some 1 mL designs (especially tuberculin style or those labeled low dead space) have a plunger that extends into the tip to minimize wasted space